Valencia turned up the heat on Atletico Madrid in the fight for third place in La Liga when a 3-0 derby victory at home to Levante on Monday lifted the Singapore-owned club to within a point of the champions with seven games left.
Manchester United, buoyed by five successive Premier League victories, head into Sunday's derby against Manchester City a place and a point above their rivals and believing they are poised to restore red ascendancy in the city.
Manchester United forward Robin van Persie is unlikely to be fit for the Premier League derby match against Manchester City later this month, manager Louis van Gaal said on Friday.
Tottenham manager Mauricio Pochettino has said Ajax have an unfair advantage because the whole of the Dutch league programme was postponed to help Erik ten Hag's side prepare.
Barca feel familiar February blues as tiredness sets in
Talking points from this weekend's Premier League action as top two Manchester City and Liverpool both won with City remaining a point clear with two games remaining.
News of all that's transpired on and off the football field
Gabriel Jesus came off the bench to secure Manchester City a 1-0 English Premier League victory at Leicester City after yet another penalty miss by Pep Guardiola's side on Saturday. Chelsea's Olivier Giroud and Marcos Alonso returned to the starting lineup to stunning effect by grabbing a goal apiece in a crucial 2-1 home win over Tottenham Hotspur in the battle between the London rivals for fourth place.
Such is the level of consistency of Manchester City (nine straight wins) and Liverpool (five straight victories), that it can be easy to lose sight of just how good this title race is.
La Liga leaders Barcelona drew 0-0 at Huesca on Saturday and are nine points clear of second-placed Atletico Madrid, who cut the gap by beating Celta Vigo 2-0.
The draw means second-placed Atletico Madrid could close the 12-point gap with Barcelona, who are on 74 points, if they beat Celta Vigo later on Saturday.
News of all that's transpired on and off the football field
Take part in this fun poll now!
News of all that's transpired on and off the football field
Barcelona beat local rivals Espanyol 2-0 in the Catalan derby on Saturday to maintain their 10 point lead at the top of La Liga, while Real Madrid scraped a 3-2 win against bottom side Huesca on Sunday.
All the results from the I-League and ISL matches played on Thursday
This and more from the happenings in the world of football
Ahead of the all-important clash, Rediff.com looks at five memorable derbies between the fierce rivals.
After seven consecutive league defeats, and one point from the last 30 on offer, had plunged Villa into crisis and cost Tim Sherwood his job, the former European champions produced a gritty display to frustrate City.
A stoppage time goal by a heavily-bandaged Martin Skrtel spared Liverpool another deflating defeat as they drew 2-2 at home to Arsenal in the Premier League.
Adam Johnson's late winner earned Sunderland a 1-0 victory over Newcastle United.
Real Madrid's teenage Brazilian duo Vinicius Junior and Rodrygo Goes sent them top of La Liga as both scored in a 2-0 win over Osasuna on Wednesday.
Jose Mourinho will select a strong Chelsea side out of respect to high-flying Championship team Derby County when they meet in the quarter-finals of the Capital One Cup on Tuesday.
Here are five talking points from the final weekend of the Premier League season:
She lived for two-thirds of her life in India, adopted its national cause and customs, and took an Indian passport. She served a prison sentence in Lahore as part of Gandhi's protests against an Imperial power which happened to be her motherland. Freda Bedi delighted in confounding accepted definitions of identity.
The following are talking points from the weekend's Premier League action:
Wayne Rooney, who has scored more goals than anyone in the Manchester derby, is back after suspension and fit for Sunday's meeting between the city's two biggest clubs at the Etihad Stadium.
The 51-year-old was a member of the Croatian team that finished third in the 1998 World Cup.
English Premier League leaders Liverpool will need to maintain their excellent recent record against Everton in Sunday's Merseyside derby if they are to hold their advantage over second-placed Manchester City.
Whatever happens in the title battle between Manchester City and Liverpool, which will go down to the final day of the season
Jermain Defoe made himself an instant Sunderland hero with a sensational volleyed goal to seal a vital 1-0 win over North East rivals Newcastle United in the Premier League on Sunday.
News of all that's transpired on and off the football field
Lionel Messi scored one penalty and missed another as Barcelona beat Real Valladolid 1-0 on Saturday to open up a seven-point lead at the top of La Liga.
Defeat left United in sixth spot, three points behind fourth-placed Chelsea, who they face this weekend.
Pep Guardiola said Manchester United's home ground Old Trafford is no longer the fortress it used to be as City look to win all three points and take the lead in the Premier League title race.
Here are five talking points from the weekend in La Liga:
News of all that's transpired on and off the football field
The fire broke out at Ninho do Urubu, a state-of-the-art training centre that was expanded and opened only two months ago.
Barcelona beat Girona 2-0 in a Catalan derby on Sunday to maintain their five-point lead at the top of La Liga, while Real Madrid thrashed Espanyol 4-2.
IMAGES from the English Premier League matches played on Tuesday